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The secret: antioxidant power

Antioxidants, found in nature, have cell-renewing effects. And the key to youthful beauty is renewal. Because every day we age. Besides the physical signs, the following process takes place in our cells:

Our cells are damaged by free radicals, which we do not need to be exposed to toxins from an external source to release, because our bodies produce free radicals. In fact, some free radicals play key roles in small amounts. Therefore, it is good not to produce too many free radicals in the body, and this can be helped by lifestyle changes and supplementation.

And damage will age the tissue. If it affects the skin, it will lead to inflexibility, wrinkles and dryness.¹ If it affects a protein called keratin in the hair, it will cause fragmentation. If it affects an organ, it may also be associated with increased outward signs of ageing.

And toxins, or free radicals, are counteracted by antioxidants.² Many vitamins and minerals also have antioxidant effects, and many herbs have detoxifying properties.

The most important antioxidants for our beauty:

• Multivitamins and minerals: a lack of any essential vitamin and mineral will age you.^3,4 Therefore, the first and most important thing is a quality multivitamin and complex mineral supplement that does not contain excessive amounts of B vitamins. Because vitamin B can make you hungrier.⁵ Of course, this is only important if we often monitor the scale.

• Zinc: due to its metallic nature, it is an especially good antioxidant.^6,7 It can also affect the hormonal system: higher amounts of zinc can inhibit the production of dihydro-testosterone (DHT) resulting from the breakdown of testosterone.⁸ And higher levels of DHT can be associated with a number of skin problems.⁹ So the reduced DHT level also reduces the number of acne. Also, zinc effectively strengthens the hair follicles and is also effective against hair loss. ¹⁷

• Grape seed extract: the resveratrol in it is an anti-aging antioxidant,¹⁰ which studies have shown can increase the quantity and quality of hereditary material.¹¹ Preservation of the genetic stock is also essential for slowing down aging. This is because ultimately all physical processes are determined by the quality of the genetic material.

• Turmeric: it detoxifies in several ways (indirectly and directly), that is, it fights against free radicals.^12,13 It also increases the level of the "happiness hormone" serotonin. ¹⁴ So it protects against wrinkles and gives balance to the skin.

• Aloe Vera: contains more than 75 different active ingredients, including vitamins, minerals, polyphenols with strong antioxidant effects and plant hormones.^15,16 Some of its active ingredients have particularly effective cell healing effects. Due to the many active ingredients, it can be widely used through the skin, also for the purpose of reducing inflammation and soothing the skin.

Collagen: the engine of beauty

There is no elastic skin without collagen. Our skin, nails and hair (also) contain a lot of collagen.

Type I collagen mostly accumulates in the skin.¹⁸ Therefore, when supplementing food, make sure to choose one that contains a large amount of this. Collagen is one of the proteins. A protein such as albumin in eggs or casein in milk. Therefore, larger amounts: 5-10 grams would be needed to achieve optimal effects. ¹⁹ It is better to consume collagen as a powder.

It is also worth combining with vitamin C and hyaluronic acid. Vitamin C is essential for the production of collagen.²⁰ Therefore, if there is not enough vitamin C, it is pointless to take collagen, because it cannot be used when it is digested - that is, reach the skin.

And hyaluronic acid is a natural substance (the main source of which is the comb of chicken or rooster).²¹ By binding water, it hydrates and moisturizes the skin and thereby smoothes it.²² Furthermore, similar to resveratrol (grape seed extract), it also has anti-aging effects. ²³

Primose oil that does not disappoint in its name

The anti-inflammatory gamma-linolenic acid (GLA) in it is responsible for its skin-regenerating properties, which is a fatty acid - the "fat" of the sedge plant.

Since it is anti-inflammatory, it can improve many skin diseases, and when applied topically, it soothes the damaged surface, similar to aloe vera. ²⁷

It is a component of skin cells and contributes to the smoothness, firmness and health of the skin when used orally through its antioxidant effects. Our body cannot produce GLA on its own, so its external intake may be justified.^24-26

Based on these, our TOP beauty care products:

1. PURITAN'S PRIDE ZINC FOR ACNE (100 TABLETS)
2. PURITAN'S PRIDE GRAPESEED EXTRACT 100 MG (50 CAPSULES)
3. PURITAN'S PRIDE TURMERIC CURCUMIN 1000 MG WITH BIOPERINE 5 MG (60 CAPSULES)
4. RULE1 COLLAGEN PEPTIDES (56 SERVINGS, UNFLAVORED)
5. NEOCELL HYALURONIC ACID 100 MG (60 CAPSULES)

Used sources:

1. West MD. The Cellular and Molecular Biology of Skin Aging. Arch Dermatol. 1994;130(1):87–95.
2. Lobo V, Patil A, Phatak A, Chandra N. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn Rev. 2010;4(8):118-126.
3. Thomas DR. Vitamins in aging, health, and longevity. Clin Interv Aging. 2006;1(1):81-91. doi:10.2147/ciia.2006.1.1.81
4. Berridge MJ. Vitamin D deficiency accelerates ageing and age-related diseases: a novel hypothesis. J Physiol. 2017;595(22):6825-6836. doi:10.1113/JP274887
5. Zhou SS, Zhou Y. Excess vitamin intake: An unrecognized risk factor for obesity. World J Diabetes. 2014;5(1):1-13. doi:10.4239/wjd.v5.i1.1
6. Prasad AS. Zinc is an Antioxidant and Anti-Inflammatory Agent: Its Role in Human Health. Front Nutr. 2014;1:14. Published 2014 Sep 1.
7. Prasad AS. Zinc: an antioxidant and anti-inflammatory agent: role of zinc in degenerative disorders of aging. J Trace Elem Med Biol. 2014 Oct;28(4):364-71.
8. Netter A, Hartoma R, Nahoul K. Effect of zinc administration on plasma testosterone, dihydrotestosterone, and sperm count. Arch Androl. 1981 Aug;7(1):69-73.
9. Lai JJ, Chang P, Lai KP, Chen L, Chang C. The role of androgen and androgen receptor in skin-related disorders. Arch Dermatol Res. 2012;304(7):499-510. doi:10.1007/s00403-012-1265-x
10. Baxter RA. Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation. J Cosmet Dermatol. 2008 Mar;7(1):2-7
11. Nikolina Škrobot Vidaček, Lucia Nanić, Sanda Ravlić, Mary Sopta, Marko Gerić, Goran Gajski, Vera Garaj-Vrhovac, Ivica Rubelj, Telomeres, Nutrition, and Longevity: Can We Really Navigate Our Aging?, The Journals of Gerontology: Series A, Volume 73, Issue 1, January 2018, Pages 39–47, https://doi.org/10.1093/gerona/glx082
12. Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytother Res. 2016 Aug;30(8):1243-64
13. Vollono L, Falconi M, Gaziano R, et al. Potential of Curcumin in Skin Disorders. Nutrients. 2019;11(9):2169. Published 2019 Sep 10.
14. Kulkarni SK, Dhir A. An overview of curcumin in neurological disorders. Indian J Pharm Sci. 2010;72(2):149-154.
15. Sánchez M, González-Burgos E, Iglesias I, Gómez-Serranillos MP. Pharmacological Update Properties of Aloe Vera and its Major Active Constituents. Molecules. 2020;25(6):1324. Published 2020 Mar 13.
16. Feily A, Namazi MR. Aloe vera in dermatology: a brief review. G Ital Dermatol Venereol. 2009 Feb;144(1):85-91. PMID: 19218914.
17. Almohanna HM, Ahmed AA, Tsatalis JP, Tosti A. The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatol Ther (Heidelb). 2019;9(1):51-70.
18. https://parjournal.net/article/view/3863
19. Choi FD, Sung CT, Juhasz ML, Mesinkovsk NA. Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. J Drugs Dermatol. 2019 Jan 1;18(1):9-16. PMID: 30681787.
20. https://www.sciencedirect.com/topics/engineering/collagen-synthesis
21. https://www.researchgate.net/publication/262629818_Purification_and_characterization_of_hyaluronic_acid_from_chicken_combs
22. Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258. doi:10.4161/derm.21923
23. Bukhari SNA, Roswandi NL, Waqas M, Habib H, Hussain F, Khan S, Sohail M, Ramli NA, Thu HE, Hussain Z. Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects. Int J Biol Macromol. 2018 Dec;120(Pt B):1682-1695.
24. Sergeant S, Rahbar E, Chilton FH. Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. Eur J Pharmacol. 2016;785:77-86.
25. Kawamura A, Ooyama K, Kojima K, Kachi H, Abe T, Amano K, Aoyama T. Dietary supplementation of gamma-linolenic acid improves skin parameters in subjects with dry skin and mild atopic dermatitis. J Oleo Sci. 2011;60(12):597-607.
26. Simon D, Eng PA, Borelli S, et al. Gamma-linolenic acid levels correlate with clinical efficacy of evening primrose oil in patients with atopic dermatitis. Adv Ther. 2014;31(2):180-188.
27. Silva JR, Burger B, Kühl CMC, Candreva T, Dos Anjos MBP, Rodrigues HG. Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair. Mediators Inflamm. 2018;2018:2503950. Published 2018 Apr 12.